Transformative Antifungal Solutions for Health

Introduction

Fungal infections pose significant challenges across industries—from agriculture to healthcare. These infections not only threaten crops and food security but also impact human and animal health. Our patented antifungal composition offers a powerful, safe, and effective solution for combating fungal threats in diverse applications. With a focus on safety and broad-spectrum efficacy, this antifungal technology provides industries with an indispensable tool to improve outcomes, enhance product longevity, and safeguard health.

The Need for Superior Antifungal Solutions

Fungal infections are a persistent issue in both agriculture and healthcare. In the agricultural sector, fungal diseases can devastate crops, reducing yields and causing significant economic losses. Meanwhile, in human and animal health, fungal infections can lead to difficult-to-treat diseases, some of which may be resistant to existing treatments.

In the pharmaceutical industry, the development of new antifungal agents has lagged behind the emergence of resistant fungal strains, making it difficult to address evolving threats. Both healthcare providers and agricultural producers are searching for solutions that offer better efficacy, safety, and adaptability to combat fungal threats across multiple applications.

Why Choose Our Antifungal Solutions for Health?

Our patented antifungal composition provides a breakthrough in the fight against fungal infections. Whether used in agriculture, human healthcare, or veterinary medicine, this technology offers a robust, reliable defense against a wide range of fungal pathogens. The composition is designed to work effectively on plants, animals, and humans, making it a versatile solution that can meet the demands of various industries.

The composition’s safety profile is another key advantage, offering an antifungal treatment that minimizes harm to non-target organisms, including humans and animals. This broad-spectrum antifungal agent is effective against a range of fungal species, providing the coverage needed to address both existing and emerging threats.

For agriculture, this composition can be applied to crops to protect against fungal diseases, helping to boost yields and reduce losses. In healthcare and veterinary applications, it offers a new treatment option for difficult-to-treat infections, ensuring faster recovery and better patient outcomes.

Key Benefits

Broad-Spectrum Efficacy: Effective against a wide range of fungal pathogens, in agriculture, human, and animal health.
Safe and Reliable: Offers a strong safety profile, ensuring minimal side effects in human, animal, and crop applications.
Versatile Applications: Ideal for use in healthcare, agriculture, and veterinary fields, providing adaptable antifungal protection.
Improved Outcomes: Helps protect crops, treat infections, and safeguard health across multiple sectors.

Deliver Safer, Stronger Antifungal Solutions

Licensing this antifungal technology offers companies in agriculture, healthcare, and pharmaceuticals an opportunity to lead with superior solutions for combating fungal infections. With its broad-spectrum effectiveness and safe application, this composition provides a critical tool for protecting health, enhancing yields, and improving overall outcomes.

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Abstract
Claims

The presently disclosed subject matter relates generally to antifungal nanofibrous materials and the use of such materials.

The invention claimed is:

1. A method for the antifungal treatment of a surface comprising: providing a surface exposed to a fungus or contaminated with a fungus; and applying a composition comprising an antifungal effective amount of nanofibers of polyacrylonitrile having antifungal activity to the surface, wherein the antifungal effective amount is an amount sufficient to inhibit growth of fungus on the surface and such that the optical density at 600 nanometers (OD₆₀₀) of a solution of fungi exposed to the nanofibers of polyacrylonitrile of the composition is no more than about 75% of the OD₆₀₀of a solution of fungi not exposed to said nanofibers, wherein the nanofibers of polyacrylonitrile are the only components of the composition that have the antifungal activity.

2. The method of claim 1, wherein the antifungal treatment comprises inhibiting or preventing fungal growth on the surface.

3. The method of claim 1, wherein the nanofibers are electrospun polyacrylonitrile nanofibers.

4. The method of claim 1, wherein the surface is porous, semi-porous or non-porous.

5. The method of claim 1, wherein the surface is metal, wall board, ceiling tile, paper, textile, concrete, stone, brick, wood, plastic, ceramic, or leather.

6. The method of claim 1, wherein the surface is a textile.

7. The method of claim 1, wherein the surface is a garment, bedding, or a part of a shoe.

8. The method of claim 5, wherein the nanofibers are electrospun polyacrylonitrile nanofibers.

9. The method of claim 1, wherein the surface is a fibrous material and the nanofibers are electrospun polyacrylonitrile nanofibers.

10. The method of claim 6, wherein the nanofibers are electrospun polyacrylonitrile nanofibers.

Title

Antifungal compositions and methods of use thereof

Inventor(s)

Lifeng Zhang, Dennis R. LaJeunesse, Nafisa Sirelkhatim

Assignee(s)

North Carolina A&T State University, University of North Carolina at Greensboro

Patent #

10412962

Patent Date

September 17, 2019