Respiratory diseases are among the leading causes of death and disability worldwide, with conditions like asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis affecting millions of people. Current treatments often focus on managing symptoms rather than addressing the underlying biological processes that exacerbate these diseases. Our patented enzyme-based therapy offers a groundbreaking approach to airway treatment by targeting mucus buildup and airway inflammation at its source. This innovative method improves airflow, reduces infection risks, and enhances overall respiratory health.
For patients with respiratory conditions, airway obstruction caused by thick mucus and inflammation is a significant challenge. Standard treatments, such as bronchodilators, corticosteroids, and mucus-thinning agents, often provide temporary relief but fail to address the root causes of airway obstruction. Moreover, many treatments come with side effects, such as immune suppression or tolerance development over time. Patients and healthcare providers are seeking more effective and targeted therapies that not only alleviate symptoms but also improve long-term lung function and quality of life.
Our patented composition and method introduce an enzyme-based treatment specifically designed for administration to a subject’s airway. The enzyme works by breaking down mucus and reducing inflammation in the respiratory tract, allowing for clearer airways and better oxygen exchange. This technology is particularly effective in conditions where excess mucus production and thickened secretions are a problem, such as cystic fibrosis, COPD, and chronic bronchitis.
By reducing mucus viscosity and controlling inflammation at the enzymatic level, this method improves airflow and reduces the frequency of infections that are often caused by trapped bacteria in stagnant mucus. The enzyme therapy is delivered directly to the airway, ensuring targeted action where it is needed most. Its localized delivery also minimizes the systemic side effects commonly seen with oral or systemic medications.
Licensing this enzyme-based airway treatment technology provides pharmaceutical and healthcare companies with a powerful tool to develop more effective therapies for respiratory diseases. By addressing mucus buildup and inflammation at the source, this technology offers a more targeted, patient-friendly solution that could dramatically improve respiratory care outcomes.
What is claimed is:
Compositions and methods for administration of an enzyme to a subject's airway
Robert O. Williams, IIISteven Idell
University of Texas System
11033611
June 15, 2021
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